Jitendra Lab !

We developed Setu: a groundbreaking bioinformatics pipeline designed to streamline the assembly of SARS-CoV-2 genomes. Addressing the challenges posed by the rapid spread of SARS-CoV-2 and the emergence of new variants, Setu is engineered to be both robust and user-friendly, making it accessible to a wider range of laboratories, including those with limited computational resources. Setu integrates a suite of open-source tools to offer a comprehensive solution for de novo genome assembly, ensuring high-quality assemblies consistently.

The pipeline is optimized for speed without compromising accuracy, crucial for timely public health responses. Designed with scalability in mind, Setu can be deployed in settings with varying computational power, making it valuable for resource-limited settings. The deployment of Setu is expected to significantly enhance the capacity for genomic surveillance of SARS-CoV-2, enabling more laboratories to participate in genome sequencing efforts, leading to better tracking of variant emergence and spread. Setu represents a significant advancement in viral genomics, offering a robust, efficient, and accessible tool for SARS-CoV-2 genome assembly. For more detailed information, the full article is available on PubMed @
https://journals.asm.org/doi/10.1128/mra.00237-24

Github @ https://github.com/jnarayan81/setu